Cyclisation of 1-(2-hydroxyphenyl)-3-substituted phenylprop-2-en-1-ones (1a-h) in pyridine with mercuric acetate gave different 2-benzylidene-1-benzofuran-3(2H)-ones (2a-h) which on subsequent reaction with hydroxylamine hydrochloride afforded 2-benzylidene-1-benzofuran-3(2H)-one oximes (3a-h). These oximes on reaction with benzoylchloride /p-toluene sulphonyl chloride gave two series of compounds 4a-h and 5a-h.The synthesized compounds have been characterized by physical and spectral data. All the compounds have been screened for antileukemic and antibacterial activities.
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